In the past 20 years, my country’s hygienic insecticides have developed rapidly. First, due to the introduction of many new varieties and advanced technologies from abroad, and second, the efforts of relevant domestic units have enabled most of the main raw materials and dosage forms of hygienic insecticides to be produced. and mention high quality and development of new types of drug development. Although there are many types of pesticide raw materials, as far as sanitary pesticides are concerned, pyrethroids are still the main ones currently used. Because pests have developed different degrees of resistance to pyrethroids in some areas, and there is cross-resistance, which affects its use. However, because it has many unique advantages such as low toxicity and high efficiency, it is difficult to be replaced by other varieties within a certain period of time. Commonly used species are tetramethrin, Es-bio-allethrin, d-allethrin, methothrin, pyrethrin, permethrin, cypermethrin, beta-cypermethrin, deltamethrin and rich dextramethrin Allethrin etc. Among them, the rich D-trans allethrin is independently developed and produced in my country. The acid part of common allethrin is separated from the cis and trans isomers and the left and right isomers are separated to increase the ratio of its effective body, thereby improving Product efficacy. At the same time, the invalid body is converted into a valid body, further reducing the cost. It marks that the production of pyrethroids in my country has entered the field of independent development and entry into the field of stereochemistry and high optical activity technology. Dichlorvos among organophosphorus insecticides is the species with the largest yield and widest application due to its strong knockdown effect, strong killing ability and natural volatilization function, but DDVP and chlorpyrifos have been restricted in use. In 1999, Hunan Research Institute of Chemical Industry, according to the recommendation of WHO, developed a broad-spectrum, quick-acting insecticide and acaricide pirimiphos-methyl, which can be used to control mosquitoes, flies, cockroaches and mites.
Among the carbamates, propoxur and Zhongbucarb are used in large amounts. However, according to relevant data, the decomposition product of sec-butacarb, methyl isocyanate, has toxicity problems. This product was not included in the list of household sanitation insecticide products published by the World Health Organization in 1997, and except China, no other country in the world has used this product for household sanitation insecticide products. In order to ensure the safety of household sanitation insecticides and be in line with international standards, the Pesticide Control Institute of the Ministry of Agriculture combined with my country’s national conditions, on March 23, 2000,for Zhongbuwei, the relevant regulations for the gradual transition to the cessation of use in household sanitation insecticides have been made.
There are many researchers on insect growth regulators, and there are many varieties, such as: diflubenzuron, diflubenzuron, hexaflumuron, etc. In some areas, they are used to control larvae in mosquito and fly breeding sites, and have achieved good results. They are being gradually popularized and applied.
In recent years, units such as Fudan University have researched and synthesized housefly pheromones, and Wuhan University has independently developed cockroach parvoviruses. These products have broad application prospects. Microbial insecticide products are under development, such as: Bacillus thuringiensis, Bacillus sphaericus, cockroach virus and Metarhizium anisopliae have been registered as sanitary products. The main synergists are piperonyl butoxide, octachlorodipropyl ether, and synergist amine. In addition, in recent years, due to the problem of the application prospect of octachlorodipropyl ether, Nanjing Forestry Research Institute extracted AI-1 synergist from turpentine, and Shanghai Entomology Research Institute and Nanjing Agricultural University developed a 94o synergist. agent. There are also follow-up synergistic amines, synergists, and the development of S-855 plant-derived synergists.
At present, there are a total of 87 active ingredients of pesticides in the effective status of sanitary insecticide registration in our country , of which: 46 (52.87%) of pyrethroids, 8 (9.20%) of organophosphorus, 5 of carbamates 1 (5.75%), 5 inorganic substances (5.75%), 4 microorganisms (4.60%), 1 organochlorine (1.15%), and 18 other types (20.68%).
Post time: Mar-20-2023