Chinese wholesale Herbs Containing Volatile Oils - Natural Coumarin Osthole from Medicinal Plants – SENTON

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Chinese wholesale Herbs Containing Volatile Oils - Natural Coumarin Osthole from Medicinal Plants – SENTON Detail:

Basic Info

Model No.: CAS No.:484-12-8

Raw Material: Plants

Additional Info

Packaging: 25KGS/Drum, or as Custimised requirement

Productivity: 1000 tons/year

Brand: SENTON

Transportation: Ocean,Land,Air

Place of Origin: China

Supply Ability: 1000 tons/year

Certificate: ISO90001, FDA

Port: Shanghai,Tianjin,Qingdao

Product Description

Osthole is a natural coumarin that was first isolated from several medicinal plants, including C. monnieri and A. pubescens.1 It is reported to induce a nonspecific elevation of cAMP and cGMP levels through its ability to inhibit phosphodiesterases, which leads to a modulation of calcium channel signaling and vasorelaxant effects. Osthole exhibits immunomodulatory, antioxidative, and anti-inflammatory properties, by regulating the expression of TNF-α, NF-κB, TGF-β, cyclooxygenases, leukotrienes, nitric oxide, ERK, and JNK. It also demonstrates antifibrotic effects in both hepatic and myocardial tissues and has been suggested to be a natural activator of defective delta F508-cystic fibrosis transmembrane conductance regulator chloride channel gating.

Product Name	Osthole
CAS No.	484-12-8
Chemical formula	C15H16O3
Molar mass	244.290 g·mol−1

Leads to Modulation of Calcium

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