China wholesale Eucalyptus Oil - Natural Coumarin Osthole from Medicinal Plants – SENTON

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China wholesale Eucalyptus Oil - Natural Coumarin Osthole from Medicinal Plants – SENTON Detail:

Product Name	Osthole
CAS No.	484-12-8
MF	C15H16O3
MW	244.290 g·mol−1
Boiling point	396.7℃
Melting point	82.0-86℃

Packaging:	25KG/Drum, or as Custimised requirement
Productivity:	1000 tons/ year
Brand:	SENTON
Transportation:	Ocean,Air，Land
Place of Origin:	China
Certificate:	ISO9001，FDA
HS Code:	29335990.13
Port:	Shanghai,Qingdao,Tianjin

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Osthole is a natural coumarin that was first isolated from several medicinal plants, including C. monnieri and A. pubescens.1 It is reported to induce a nonspecific elevation of cAMP and cGMP levels through its ability to inhibit phosphodiesterases, which leads to a modulation of calcium channel signaling and vasorelaxant effects. Osthole exhibits immunomodulatory, antioxidative, and anti-inflammatory properties, by regulating the expression of TNF-α, NF-κB, TGF-β, cyclooxygenases, leukotrienes, nitric oxide, ERK, and JNK. It also demonstrates antifibrotic effects in both hepatic and myocardial tissues and has been suggested to be a natural activator of defective delta F508-cystic fibrosis transmembrane conductance regulator chloride channel gating.

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