China OEM Plant Extracts For Varicose Veins - Natural Coumarin Osthole from Medicinal Plants – SENTON
China OEM Plant Extracts For Varicose Veins - Natural Coumarin Osthole from Medicinal Plants – SENTON Detail:
Basic Info
Model No.: CAS No.:484-12-8
Raw Material: Plants
Additional Info
Packaging: 25KGS/Drum, or as Custimised requirement
Productivity: 1000 tons/year
Brand: SENTON
Transportation: Ocean,Land,Air
Place of Origin: China
Supply Ability: 1000 tons/year
Certificate: ISO90001, FDA
Port: Shanghai,Tianjin,Qingdao
Product Description
Osthole is a natural coumarin that was first isolated from several medicinal plants, including C. monnieri and A. pubescens.1 It is reported to induce a nonspecific elevation of cAMP and cGMP levels through its ability to inhibit phosphodiesterases, which leads to a modulation of calcium channel signaling and vasorelaxant effects. Osthole exhibits immunomodulatory, antioxidative, and anti-inflammatory properties, by regulating the expression of TNF-α, NF-κB, TGF-β, cyclooxygenases, leukotrienes, nitric oxide, ERK, and JNK. It also demonstrates antifibrotic effects in both hepatic and myocardial tissues and has been suggested to be a natural activator of defective delta F508-cystic fibrosis transmembrane conductance regulator chloride channel gating.
Product Name | Osthole |
CAS No. | 484-12-8 |
Chemical formula | C15H16O3 |
Molar mass | 244.290 g·mol−1 |
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